The Gunners were beaten 3-1 on their home patch in the first leg of their Champions League last-16 tie with Monaco in February, and host the Hammers ahead of the second leg next week.
Song, who played for Arsenal between 2005 and 2012, has called on his West Ham teammates to emulate the French outfit on Saturday.
"I think Monaco was how you want to play when you play in the Emirates," he told the club's official website.
"I know this stadium very well and I know when you play with Arsenal it's very hard.
"If you want to go to Emirates and try to play you will not have any chance to win the game there because this stadium is very hard to play in.
"You have to stay together very compact and not give them any room, then take the opportunity on the counter attack.
"If we do this very well like Monaco did, then we can get a good result there."