Chelsea midfielder Mikel was dropped for last month's CAF Africa Cup of Nations qualifier in Tanzania, while his team-mate Moses, currently on loan to West Ham, missed out through injury. Watford striker Ighalo was not considered while Lazio midfielder Ogenyi Onazi was sidelined by a one-match suspension picked up against Chad in June, when he was sent off.
The winners of the preliminary round between Swaziland and Djibouti will host the Super Eagles on 9 November in a World Cup first-round qualifier. Nigeria will host the return leg at home eight days later.
Goalkeepers: Vincent Enyeama (Lille/FRA), Carl Ikeme (Wolverhampton Wanderers/ENG), Ikechukwu Ezenwa (Sunshine Stars), Femi Thomas (Enyimba)
Defenders: Leon Balogun (FSV Mainz 05/GER), Abdullahi Shehu (Uniao da Madeira/POR), Elderson Echiejile (AS Monaco/FRA), Chima Akas (Sharks FC), Godfrey Oboabona (Caykur Rizespor/TUR), William Troost Ekong (FK Haugesund/NOR), Kenneth Omeruo (Kasimpasa SK/TUR), Austin Oboroakpo (Abia Warriors)
Midfielders: Ogenyi Onazi (SS Lazio/ITA), Paul Onobi (Sunshine Stars), Obiora Nwankwo (Coimbra FC/POR), Mikel Obi (Chelsea/ENG), Rabiu Ibrahim (AS Trencin/SLO)
Forwards: Ahmed Musa (CSKA Moscow/RUS), Emmanuel Emenike (Al Ain/UAE), Sylvester Igbonu (FC UFA/RUS), Moses Simon (KAA Gent/BEL), Victor Moses (West Ham United/ENG), Odion Ighalo (Watford FC/ENG), Prince Aggrey (Sunshine Stars)