Boxing fans around the world can view the action from 20:30 (GMT +5) at https://www.youtube.com/user/AIBAproboxingTV.
Abdrakhmanov has amassed a flawless 4-0 record in APB, and defeated Tojibaev over eight rounds last January to become Champion.
Despite holding the coveted Lightweight title, Abdrakhmanov will travel into his challengers backyard to defend his belt, but is sanguine regarding his chances.
“I have never lost in APB, and will keep my perfect record after beating Tojibaev once again,” he said.
“We have both been training exceptionally hard for this title match, and it will be one of the best matches of the year. Fighting away from home only makes me more motivated to return to Kazakhstan with my title belt.”
Tojibaev has won five of his six APB matches, and has been in outstanding form since his initial title defeat to Abdrakhmanov.
Cycle I victories over David Oliver Joyce (IRE) and Dmitriy Polyanskiy (RUS) have propelled the Beijing 2008 Olympian back into the title picture, much to the delight of his legion of supporters in Uzbekistan.
“The support I have received from my fans in Uzbekistan ahead of this match has been incredible. My recent form has been excellent, and I anticipate that it will continue against Abdrakhmanov,” remarked the challenger.
“Yes I have lost to him before, but I learnt a great deal from that bout, and I believe fighting over 12 rounds will prove to be an advantage for me.”
Although Tojibaev lost his first match with Abdrakhmanov, he impressed towards the latter stages of the bout, and will have four more rounds to press home his stamina in Tashkent.
The Champion is a supremely gifted fighter who has blistering hand speed and focused defence which is helped by rapid reflexes.
He shall have to navigate his way through the awkward style of Tojibaev however, and the challenger has carved out an impressive style in APB which involves plenty of movement.
Three further Uzbek fighters feature on the undercard, as Khakberdiev Ulugbek meets Lazar-ioan Nichita (ROU), Abdullayev Shukhrat fights Margineanu Alexandru Bibiricea (ROU) and Ulugbek Mubinov battles Milutin Stankovic (SRB).