The four newcomers are goalkeeper David Peterson of Tigers, defender Heita Immanuel and Riaan Hanamub of Black Africa and Orlando Pirates respectively, and Oswaldo Xamseb of Tura Magic.
Namibia sits at the bottom of Group K with no point after two matches, and will travel to Bujumbura for the Day 3 clash on Saturday, 26 March 2016 before hosting the return three days later in Windhoek.
The Teranga Lions of Senegal occupy the top of the standings on six points, with Burundi and Niger in that order on three points apiece.
Mannetti appears to have given up in the race for a place at next year’s continental showpiece event in Gabon, after defeats from their previous two games.
“At the beginning of these qualifiers, I said it was difficult to challenge Senegal for the top spot and now we have three crucial games in which to redeem ourselves. We must and can beat Burundi away on 26 March and then against at home on 29 March”, Mannetti was quoted by the Namibia Football Association website.
Goalkeepers: Loydt Kazapua (African Stars), Maximillian Mba Golden Arrows, South Africa), Edward Maova (Civics), David Peterson (Tigers), Aluis Charles Uirab (Orlando Pirates)
Defenders: Denzil Haoseb (Black Africa), Chris Katjiukua (Golden Arrows, South Africa), Willem Mwedihanga (University of Pretoria, South Africa), Romario Ndjavera (Tigers), Denis Ngueza Tjetjinda (African Stars), Ferdinand Karongee (Tigers), Edmund Kambanda (UNAM), Riaan Hanamub (Orlando Pirates), Oswaldo Xamseb (Tura Magic)
Midfielders: Peter Shalulile (Highlands Park, South Africa), Dynamo Fredericks (Black Africa), Willy Stephanus (Black Africa), Benyamen Nenkavu (Tigers), Absalom Iimbondi (Tigers), Heinrich Isaacks (UNAM), Petrus Shitembi (Amazulu, South Africa), Ronald Ketjijere (University of Pretoria, South Africa), Deon Hotto (Golden Arrows, South Africa), Heita Immanuel (Black Africa)
Forwards: Benson Shilongo (Gaborone United, Botswana), Hendrik Somaeb (Free State Stars, South Africa), Terdius Uiseb (Orlando Pirates)