Goalkeeper Adam Kwarasey makes a return to the Ghana squad for the first time since June 2014.
Grant named the US-based goalie in his 23-man squad for the AFCON 2017 Group H double-header against Mozambique. The Ghanaians, top of the group with the maximum six points from their opening two games will host the Mambas on Thursday, 24 March 2016 in Accra before trekking Maputo four days later for the reverse.
Also making a return to team is Sassuolo forward Alfred Duncan whilst England-based Andre Ayew and defender Phil Ofosu-Ayeh of German second division outfit, Eintracht Braunschweig were left out due to injuries.
Only two local-based players made the cut, goalkeeper Richard Ofori of Wa All Stars and midfielder Samuel Tetteh of West African Football Academy.
The Black Stars beat Mauritius 7-1 in the Group H opener in Accra before pulling a lone goal victory over Rwanda away in Kigali last September.
Goalkeepers: Razak Braimah (Cordoba, Spain), Adam Kwarasey(Portland Timbers, USA), Richard Ofori (Wa All Stars)
Defenders: Harrison Afful (Columbus Crew, USA), Daniel Amartey, (Leicester City, England), Jeffery Schlupp (Leicester City, England), Baba Rahman (Chelsea, England), John Boye (Sivasspor, Turkey), Jonathan Mensah (Anzhi, Russia), Gyimah Edwin (Orlando Pirates, South Africa)
Midfielders: Rabiu Mohammed (Krasnodar, Russia), Emmanuel Agyemang-Badu (Udinese, Italy), Afriyie Acquah (Torino, Italy), Samuel Tetteh (WAFA), Mubarak Wakaso (Las Palmas, Spain Fire, USA), Frank Acheampong (Anderlecht, Belgium), Alfred Duncan (Sussualo, Italy), Christian Atsu (Malaga, Spain)
Forwards: Asamoah Gyan (SIPG Shanghai, China), Jordan Ayew (Aston Villa, England), Abdul-Majeed Waris (Lorient, France) Ebenezer Assifuah (Sion, Switzerland), David Accam (Chicago Fire, USA)