Gayle was with the Tallawahs from 2013 to 2016, winning the title with them twice in that time. Since then he has been with the St Kitts & Nevis Patriots where he has captained them to the playoffs in successive years, making the final in 2017.
The rest of the Tallawahs squad will be decided at the Hero CPL Players Draft which takes place on 22 May.
Jefferson Miller, COO of the Jamaica Tallawahs, said: “We are delighted to have Chris playing for his home team for the 2019 season. There is no bigger name in Twenty20 cricket, and we can’t wait for him to arrive and make the Jamaican fans proud. We are looking forward to Chris being a big part of our push for a third CPL title.”