Junior Ajayi and Kingsley Sokari each scored in the second half to ensure the maximum points for the Nigerians, and go top of Group B with three points.
Nigeria dictated the pace of the game from the onset asking the Ghanaian defence several questions. Their control of the midfield led to pressure on the Black Meteors backline forcing goalkeeper Samuel Ofori, the busier of the two shot stoppers, to make a couple of saves.
Despite the dominance, there was no clear cut chance for the Nigerians in the opening half with erratic shooting upfront serving their bane.
Samson Siasia’s charges resumed on the same tempo and their efforts finally yielded dividends on 55 minutes. Aminu Umar profited from a swift counter before crossing to Ajayi, who tapped home for the opener.
Down by a goal, the Ghanaians lifted up their game but barely threatened the Nigerians, who continue to remain dangerous on the break.
Sokari sealed victory three minutes from time with the second goal, lobbing past Ofori from a Azubuike Okechukwu assist.
The winner of the group and runner-up will qualify for the semis.